The Michigan–Wacker Historic District, situated in Chicago, Illinois, is a registered National Historic Places District encompassing sections of both the Chicago Loop and the Near North Side community areas. This district is renowned for its connection to the Chicago River, featuring two prominent bridges that span it, as well as eleven high-rise and skyscraper buildings constructed during the 1920s. Several Chicago Landmark structures are among its contributing properties, including:

333 North Michigan
London Guarantee Building (85 East Wacker, Chicago Illinois 60601)
Carbide & Carbon Building (230 North Michigan)
DuSable Bridge (Formerly Michigan Avenue Bridge)
Jewelers' Building (35 East Wacker, Chicago Illinois 60601)
Mather Tower (75 East Wacker, Chicago Illinois 60601)
Tribune Tower (435 North Michigan)

Notable sites within the district also encompass Pioneer Court and the Jean Baptiste Point Du Sable Homesite (401 North Michigan). The latter holds significance as the location of Chicago's inaugural permanent residence and bears the distinction of being a National Historic Landmark. Another prominent feature is the Wrigley Building (410 North Michigan). Across the Michigan Avenue Bridge lies the former site of Fort Dearborn, an established US Army post dating back to 1803. To the west, you'll find the Heald Square Monument, which features a statue of George Washington and honors the financiers of the American Revolution.

This historic district comprises contributing properties located on North Michigan Avenue, East Wacker Drive, North Wabash Avenue, and East South Water Street. Additional streets encompassed within the district are Rush Street, Hubbard, Illinois, and Kinzie. The majority of these properties are situated on Michigan Avenue, with addresses spanning from 230 North Michigan to 505 North Michigan. The district also includes sections of Michigan, Wacker, and East South Water streets, all of which are among Chicago's multifaceted, multi-level thoroughfares. Most of the high-rise buildings and skyscrapers within this district feature architectural styles such as Gothic, Baroque, and Art Deco. It should be noted that this district lies to the north of the Historic Michigan Boulevard District and was officially listed on the National Register of Historic Places on November 15, 1978.